MAKATUSSIN SYROP SECRETS

desvenlafaxine will increase the stage or outcome of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Watch. Desvenlafaxine inhibits CYP2D6; with higher desvenlafaxine doses (ie, four hundred mg) reduce the CYP2D6 substrate dose by approximately fifty%; no dosage adjustment wanted with desvenlafaxine doses seven consecutive times